Basic information of CD58 :
| Official Symbol of Gene | CD58 |
| Species | Homo sapiens |
| Entrez Gene ID | 965 |
| Official Full Name | CD58 molecule |
| Also known as | ag3; LFA3; LFA-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000116815 MIM:153420; AllianceGenome:HGNC:1688 |
| Map Location | 1p13.1 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Poland |
| Sample Size | 174MS |
Literature information of multiple sclerosis :
| Pubmed ID | 30818222 |
| Year | 2019 |
| Title | Analysis of chosen SNVs in GPC5, CD58 and IRF8 genes in multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The study suggests that genetic variants inGPC5, CD58 and IRF8 genes may be of clinical interest in MS as predictors of age of onset and response to therapy. |
| Mechanism/Pathway | Multiple sclerosis (MS) is an autoimmune disease of the central nervous system with a neurodegen-erative compound. Heterogenetic background of autoimmunity pathway components has been suggested in the MS pathogenesis |
