Basic information of IL23R :
| Official Symbol of Gene | IL23R |
| Species | Homo sapiens |
| Entrez Gene ID | 149233 |
| Official Full Name | interleukin 23 receptor |
| Also known as | PSORS7 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000162594 MIM:607562; AllianceGenome:HGNC:19100 |
| Map Location | 1p31.3 |
| Variation Type | SNP |
| refSNP ID | rs1884444 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Chinses |
| Sample Size | 206 IDD patients and 300 normal controls |
Literature information of multiple sclerosis :
| Pubmed ID | 27893410 |
| Year | 2016 |
| Title | Characterization of variations in IL23A and IL23R genes: possible roles in multiple sclerosis and other neuroinflammatory demyelinating diseases |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We conclude that variants in IL-23A and IL-23R genes were associated with the risk of MS or other IDD diseases. |
| Mechanism/Pathway | Interleukin-23A (IL23A) regulates and coordinates the activities of immune cells by interacting with its receptor IL23R and plays key roles in the pathogenesis of immune inflammatory diseases. |
