Basic information of CIITA :

Official Symbol of Gene	CIITA
Species	Homo sapiens
Entrez Gene ID	4261
Official Full Name	class II major histocompatibility complex transactivator
Also known as	C2TA; NLRA; MHC2TA; CIITAIV
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000179583 MIM:600005; AllianceGenome:HGNC:7067
Map Location	16p13.13
Variation Type	Allele
refSNP ID	NA

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	NA
Detected Method	PCR
Disease	MS
Disease subtype	MS
Population	Northern Ireland
Sample Size	440MS/316Control

Literature information of multiple sclerosis :

Pubmed ID	29100048
Year	2007
Title	The MHC2TA –168A/G and +1614G/C polymorphisms and risk for multiple sclerosis or chronic inflammatory arthropathies

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	Carriage of 11614C was protective against JIA (OR 0.6, 95% CI 0.3–1.0) and showed a similar trend in RA and MS (OR 0.7, 95% CI 0.5–1.0; OR 0.8, 95% CI 0.6–1.0, respectively).
Mechanism/Pathway	The 2168A-G polymorphism has been shown to influence transcription of the MHC2TA gene and has been implicated in several inflammatory/autoimmune disorders.