Basic information of IL6 :
| Official Symbol of Gene | IL6 |
| Species | Homo sapiens |
| Entrez Gene ID | 3569 |
| Official Full Name | interleukin 6 |
| Also known as | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018 |
| Map Location | 7p15.3 |
| Variation Type | SNP |
| refSNP ID | rs1800795 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Czech population. |
| Sample Size | 297MS/135Control |
Literature information of multiple sclerosis :
| Pubmed ID | 30069682 |
| Year | 2018 |
| Title | Association of interleukin 6, interleukin 7 receptor alpha, and interleukin 12B gene polymorphisms with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We also showed that IL-12B A1188C (rs3212227) can contribute to the progression of the disease in the Czech population. |
| Mechanism/Pathway | Pro-inflammatory and anti-inflammatory cytokines have been shown to play a crucial role in the pathophysiology of multiple sclerosis (MS) |
