Basic information of MMP9 :
| Official Symbol of Gene | MMP9 |
| Species | Homo sapiens |
| Entrez Gene ID | 4318 |
| Official Full Name | matrix metallopeptidase 9 |
| Also known as | GELB; CLG4B; MMP-9; MANDP2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000100985 MIM:120361; AllianceGenome:HGNC:7176 |
| Map Location | 20q13.12 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 727MS/604Control |
Literature information of multiple sclerosis :
| Pubmed ID | 23897640 |
| Year | 2014 |
| Title | Common genetic variants in the plasminogen activation pathway are not associated with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No associations were found between the 17 polymorphisms and MS. Also, gene expression levels were analysed according to genotype: no associations were observed. |
| Mechanism/Pathway | Matrix metalloproteinase 9 (MMP9) is involved in multiple sclerosis (MS) aetiology. Previously, we identified differen-tial gene expression of plasminogen activation cascade genes in MS patients. |
