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Basic information of IL-12 :

Official Symbol of Gene IL-12
Species Homo sapiens
Entrez Gene ID 3593
Official Full Name interleukin 12B
Also known as CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000113302 MIM:161561; AllianceGenome:HGNC:5970
Map Location 5q33.3
Variation Type Allele
refSNP ID NA

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype MS
Population west Sicily
Sample Size 91MS220Health

Literature information of multiple sclerosis :

Pubmed ID 16803996
Year 2006
Title Search for Genetic Factors Associated with Susceptibility to Multiple Sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Genotype frequencies for all the analyzed polymorphisms were not differently distributed between cases and controls.
Mechanism/Pathway Multiple sclerosis (MS) is a cell-mediated autoimmune dis-ease characterized by type-1 cytokine production.