Basic information of MMP2 :
| Official Symbol of Gene | MMP2 |
| Species | Homo sapiens |
| Entrez Gene ID | 4313 |
| Official Full Name | matrix metallopeptidase 2 |
| Also known as | CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000087245 MIM:120360; AllianceGenome:HGNC:7166 |
| Map Location | 16q12.2 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | RRMS/PPMS/SPMS/CIS |
| Population | Caucasian and of T urkish |
| Sample Size | 102MS/102Control |
Literature information of multiple sclerosis :
| Pubmed ID | 26298319 |
| Year | 2015 |
| Title | MMP-2 polymorphism modifies the onset of optic neuritis as a first presenting symptom in MS |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The MMP-2 polymorphism led to a 5-year-earlier age of disease onset in MS patients with ON as a first symptom (p = 0.009). |
| Mechanism/Pathway | N/A |
