Basic information of IL6 :
| Official Symbol of Gene | IL6 |
| Species | Homo sapiens |
| Entrez Gene ID | 3569 |
| Official Full Name | interleukin 6 |
| Also known as | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018 |
| Map Location | 7p15.3 |
| Variation Type | SNP |
| refSNP ID | rs1800795 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS(ON) |
| Population | NA |
| Sample Size | 80MS/146Control |
Literature information of multiple sclerosis :
| Pubmed ID | 32449403 |
| Year | 2020 |
| Title | Associations between IL1RAP rs4624606, IL1RL1 rs1041973, IL-6 rs1800795, and HTRA1 rs11200638 gene polymorphisms and development of optic neuritis with or without multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our study showed that IL1RAP rs4624606, IL-6 rs1800795, and HTRA1 rs11200638 are not associated with an increased risk of developing ON. However, the IL1RL1 rs1041973 A/C genotype might be associated with an increased risk of developing ON. |
| Mechanism/Pathway | The aim of our study was to determine the associations between IL1RAP rs4624606, IL1RL1 rs1041973,IL-6 rs1800795, and HTRA1 rs11200638 gene polymorphisms and development of ON with or without MS. |
