Home Details
| Official Symbol of Gene | GFI1 |
| Species | Homo sapiens |
| Entrez Gene ID | 2672 |
| Official Full Name | growth factor independent 1 transcriptional repressor |
| Also known as | SCN2; GFI-1; GFI1A; ZNF163 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000162676 MIM:600871; AllianceGenome:HGNC:4237 |
| Map Location | 1p22.1 |
| Variation Type | SNP |
| refSNP ID | rs6680578 |
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 732MS/974Control |
| Pubmed ID | 20087403 |
| Year | 2010 |
| Title | Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis |
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | This Tag-SNP captures two SNPs in complete linkage disequilibrium (r21), both located within the 17th intron of the EVI5 gene. Our findings agree with the corresponding data of the recent IMSGC study and present new genetic evidence that points to EVI5 as a factor of susceptibility to MS |
| Mechanism/Pathway | We observed an association with MS in three of eight Tag-SNPs: rs11804321 (P0.008, OR1.29; 95% CI1.08–1.54), rs11808092 (P0.048, OR1.19; 95% CI1.03–1.39) and rs6680578 (P0.0082, OR1.23; 95% CI1.07–1.41) |

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