Basic information of GPC5 :
| Official Symbol of Gene | GPC5 |
| Species | Homo sapiens |
| Entrez Gene ID | 2262 |
| Official Full Name | glypican 5 |
| Also known as | NA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000179399 MIM:602446; AllianceGenome:HGNC:4453 |
| Map Location | 13q31.3 |
| Variation Type | SNP |
| refSNP ID | rs10492503 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | NA |
| Sample Size | 575MS |
Literature information of multiple sclerosis :
| Pubmed ID | 24943672 |
| Year | 2014 |
| Title | Prediction of response to interferon therapy in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | Genetic analysis of the studied gene variants do not provide additional information. |
| Mechanism/Pathway | Single nucleotide polymorphisms (SNPs) in the genes encoding interferon response factor (IRF)-5, IRF-8 and glypican-5 (GPC5) have been associated with disease activity in multiple sclerosis (MS) patients treated with interferon (IFN)-b. |
