Basic information of HLA-B :
| Official Symbol of Gene | HLA-B |
| Species | Homo sapiens |
| Entrez Gene ID | 3106 |
| Official Full Name | major histocompatibility complex, class I, B |
| Also known as | AS; HLAB; B-4901 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932 |
| Map Location | 6p21.33 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-SSO |
| Disease | MS |
| Disease subtype | NA |
| Population | resident Faroese |
| Sample Size | 16 MS/128Health |
Literature information of multiple sclerosis :
| Pubmed ID | 7903488 |
| Year | 1993 |
| Title | Multiple sclerosis in the Faroe Islands VI. Studies of HLA markers |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No significant deviations in antigen frequencies between MS patients and control groups were observed. |
| Mechanism/Pathway | The occurrence of CNMS in these epidemics seems therefore associated to HLA class II-linked genetic factors similar to those found in studies of other Caucasians with MS. This observation seems important in understanding the pathogenesis of this disease |
