Basic information of IL2 :
| Official Symbol of Gene | IL2 |
| Species | Homo sapiens |
| Entrez Gene ID | 3558 |
| Official Full Name | interleukin 25 |
| Also known as | IL-2; TCGF; lymphokine |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000109471 MIM:147680; AllianceGenome:HGNC:6001 |
| Map Location | 4q27 |
| Variation Type | polymorphisms |
| refSNP ID | -475 TT |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood |
| Detected Method | RFLP-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 70 patients with relapsing – remitting multiple sclerosis (RRMS) and 50 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 35765522 |
| Year | 2022 |
| Title | Correlation of -475 IL-2 Promoter Gene Polymorphisms and the Levels of Serum IL-2 on the Risk of Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our results showed that in this population of Iraqi patients, the AT genotype / A allele of -475 IL-2 promoter gene SNP may include attributed factors for MS predisposition. |
| Mechanism/Pathway | N/A |
