Basic information of GRM7 :
| Official Symbol of Gene | GRM7 |
| Species | Homo sapiens |
| Entrez Gene ID | 2917 |
| Official Full Name | glutamate metabotropic receptor 7 |
| Also known as | GLUR7; MGLU7; GPRC1G; MGLUR7; NEDSHBA; PPP1R87 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196277 MIM:604101; AllianceGenome:HGNC:4599 |
| Map Location | 3p26.1 |
| Variation Type | SNP |
| refSNP ID | rs6782011 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | West of Iran. |
| Sample Size | 397MS/400Health |
Literature information of multiple sclerosis :
| Pubmed ID | 12568117 |
| Year | 2002 |
| Title | TNF-a and -b Gene Polymorphisms in Multiple Sclerosis: A Highly Significant Role for Determinants in the First Intron of the TNF-b Gene |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | None of the estimated haplotype blocks of rs6782011 and rs779867 were associated with MS risk in the assessed population. |
| Mechanism/Pathway | Tumor necrosis factor (TNF)-a and TNF-b are proinflammatory cytokines that have been implicated in the pathogenesis of several autoimmune diseases |
