Basic information of IL4 :
| Official Symbol of Gene | IL4 |
| Species | Homo sapiens |
| Entrez Gene ID | 3565 |
| Official Full Name | interleukin 4 |
| Also known as | BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000113520 MIM:147780; AllianceGenome:HGNC:6014 |
| Map Location | 5q31.1 |
| Variation Type | VNTR (variable number tandem repeat) |
| refSNP ID | 3 VNTR (variable number tandem repeat) |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Turkish population |
| Sample Size | 125MS/1601Health |
Literature information of multiple sclerosis :
| Pubmed ID | 23756167 |
| Year | 2013 |
| Title | Association of interleukin (IL)-4 gene intron 3 VNTR polymorphism with multiple sclerosis in Turkish population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The results of this study suggest that intron 3 VNTR polymorphism of the IL-4 gene was pos-itively associated with predisposition to develop MS in Turkish population. |
| Mechanism/Pathway | Genetic risk factors are known to contribute to the etiology of multiple sclerosis (MS). Interleu-kin (IL)-4 gene polymorphisms have been associated with immune-mediated diseases. The aim of this study was to explore the frequency of IL-4 gene intron 3 VNTR (variable number tandem repeat) poly-morphism in a cohort of Turkish patients with MS. |
