Basic information of HLA-DPB1 :
| Official Symbol of Gene | HLA-DPB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3115 |
| Official Full Name | major histocompatibility complex, class II, DP beta 1 |
| Also known as | DPB1; HLA-DP; HLA-DPB; HLA-DP1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940 |
| Map Location | 6p21.32 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | NA |
| Sample Size | 52MS/29Health |
Literature information of multiple sclerosis :
| Pubmed ID | 31826574 |
| Year | 2019 |
| Title | Expression of HLA-DP in patients with neuromyelitis optica spectrum disorders |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There was no statistically significant difference of the distributions of HLA-DPB1*0501/HLA-DPB1*0501, HLA-DPB1*0501/X and X/X genotypes and the frequencies of allele of HLA-DPB1*0501 among NMOSD, MS patients and healthy controls (P=0.96 and 0.71, respectively). |
| Mechanism/Pathway | To investigate the effect of HLA-DP gene expression on the susceptibility and disease status of neuromyelitis optica spectrum disorders (NMOSD). |
