Basic information of MIF :
| Official Symbol of Gene | MIF |
| Species | Homo sapiens |
| Entrez Gene ID | 4282 |
| Official Full Name | macrophage migration inhibitory factor |
| Also known as | GIF; GLIF; MMIF |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000240972 MIM:153620; AllianceGenome:HGNC:7097 |
| Map Location | 22q11.23 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | CSF |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Turkish population |
| Sample Size | 120MS/120Health |
Literature information of multiple sclerosis :
| Pubmed ID | 20233515 |
| Year | 2010 |
| Title | Association of macrophage migration inhibitory factor gene promoter polymorphisms with multiple sclerosis in Turkish patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | This study indicates that the MIF –173 CC genotype may cause susceptibility to multiple sclerosis in the white Turkish population and a younger age of disease onset is associated with this polymorphism. |
| Mechanism/Pathway | Elevated levels of macrophage migration inhibitory factor (MIF) have been observed in the cerebrospinal fluid of patients with multiple sclerosis. |
