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Basic information of IL1B :

Official Symbol of Gene IL1B
Species Homo sapiens
Entrez Gene ID 3553
Official Full Name interleukin 1 beta
Also known as IL-1; IL1F2; IL1beta; IL1-BETA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992
Map Location IL-1; IL1F2; IL1beta; IL1-BETA
Variation Type SNP
refSNP ID rs16944

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail NA
Detected Method RT-PCR
Disease MS
Disease subtype N/A
Population NA
Sample Size NA

Literature information of multiple sclerosis :

Pubmed ID 24867167
Year 2014
Title The Analysis of Correlation between IL-1B Gene Expression and Genotyping in Multiple Sclerosis Patients

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result We found that the expression level of IL-1B in MS patients increased 3.336 times more than controls in PBMCs but the rs16944 SNP in the promoter region of IL-1B did not affect the expression level of this gene and there was not association of this SNP with MS in the examined population
Mechanism/Pathway N/A