Basic information of ICAM1 :
| Official Symbol of Gene | ICAM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3383 |
| Official Full Name | intercellular adhesion molecule 1 |
| Also known as | BB2; CD54; P3.58 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000090339 MIM:147840; AllianceGenome:HGNC:5344 |
| Map Location | 19p13.2 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | NA |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | NA |
| Sample Size | NA |
Literature information of multiple sclerosis :
| Pubmed ID | 9667594 |
| Year | 1998 |
| Title | Multiple Sclerosis: The Increased Frequency of the ICAM-1 Exon 6 Gene Point Mutation Genetic Type K469 |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The results indicate increased frequency of ICAM-1 exon 6 allele T in MS patients, which may contribute to the MS genetics background. |
| Mechanism/Pathway | Intracellular adhesion molecule-1 (ICAM-1) plays an important role in the cascade of adhesion events in the homing of inflammatory cells to the central nervous system (CNS) in experimental autoimmune encephalomyelitis (EAE) and in multiple sclerosis (MS). |
