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Basic information of ICAM1 :

Official Symbol of Gene ICAM1
Species Homo sapiens
Entrez Gene ID 3383
Official Full Name intercellular adhesion molecule 1
Also known as BB2; CD54; P3.58
Gene Type protein coding
dbXrefs Ensembl:ENSG00000090339 MIM:147840; AllianceGenome:HGNC:5344
Map Location 19p13.2
Variation Type Allele
refSNP ID NA

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype N/A
Population Slovak population
Sample Size NA

Literature information of multiple sclerosis :

Pubmed ID 28130760
Year 2016
Title Analysis of ICAM1 gene polymorphism in Slovak multiple sclerosis patients

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Our analysis revealed no statistically significant asso-ciation of ICAM1 p o l y m o r p h i s m s w i t h r i s k o f M S d e v e l o p -ment in the Slovak population.
Mechanism/Pathway Infiltration of immune cells into CNS is one of the essential events in multiple sclerosis (MS) development.Adhesion molecules like the intercellular adhesion molecule 1 (ICAM-1) play critical role in this process.