Basic information of SPP1 :
| Official Symbol of Gene | SPP1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6696 |
| Official Full Name | secreted phosphoprotein 1 |
| Also known as | OPN; BNSP; BSPI; ETA-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118785 MIM:166490; AllianceGenome:HGNC:11255 |
| Map Location | 4q22.1 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Polish population. |
| Sample Size | 100MS |
Literature information of multiple sclerosis :
| Pubmed ID | 26785368 |
| Year | 2015 |
| Title | Polymorphism of the osteopontin gene and clinical course of multiple sclerosis in the Polish population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No association of OPN with susceptibility to MS was found in the Polish population. |
| Mechanism/Pathway | Osteopontin (OPN) is a key cytokine involved in T-cell activation in multiple sclerosis (MS). |
