Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Gulf |
| Sample Size | 47MS/ |
Literature information of multiple sclerosis :
| Pubmed ID | 2425452 |
| Year | 1986 |
| Title | Association between HLA-D region epitopes and multiple sclerosis in Arabs |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Those patients from the Mediterranean area showed an association ctf MS with HLA-DR2 (p <0.001) and -DQwl (p <0.05), whilst in those from the Gulf there was an association with -DRw53 (p <0.02). |
| Mechanism/Pathway | We have studied the HLA associations of MS patients in Arab patients from two re-gions. |
