Basic information of HAVCR2 :
| Official Symbol of Gene | HAVCR2 |
| Species | Homo sapiens |
| Entrez Gene ID | 84868 |
| Official Full Name | hepatitis A virus cellular receptor 2 |
| Also known as | TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000135077 MIM:606652; AllianceGenome:HGNC:18437 |
| Map Location | N/A |
| Variation Type | SNP |
| refSNP ID | rs1036199 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RFLP-PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Isfahan |
| Sample Size | 140MS/138Health |
Literature information of multiple sclerosis :
| Pubmed ID | 29141799 |
| Year | 2017 |
| Title | The +4259A > C polymorphism of TIM-3 but not -1637C > T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Our findings suggest that +4259 A > C polymorphism in TIM-3 gene may be one of the important genetic factors associated with the MS susceptibility among Iranian populations. |
| Mechanism/Pathway | Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) which in-itiated and mediated by autoreactive T helper1 cells directed against myelin antigens. |
