Basic information of HAVCR1 :
| Official Symbol of Gene | HAVCR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 26762 |
| Official Full Name | hepatitis A virus cellular receptor 1 |
| Also known as | TIM; KIM1; TIM1; CD365; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000113249 MIM:606518; AllianceGenome:HGNC:17866 |
| Map Location | N/A |
| Variation Type | SNP |
| refSNP ID | rs7702919 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RFLP-PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Isfahan |
| Sample Size | 140MS/138Health |
Literature information of multiple sclerosis :
| Pubmed ID | 29141799 |
| Year | 2017 |
| Title | The +4259A > C polymorphism of TIM-3 but not -1637C > T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | We found that the polymorphism +4259 A > C in exon 3 of the TIM-3 gene is associated with sus-ceptibility to the MS but the other polymorphism,in the promoter region of TIM-1 is not (p= 0.064). |
| Mechanism/Pathway | Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) which in-itiated and mediated by autoreactive T helper1 cells directed against myelin antigens. |
