Basic information of LOC102724971 :
| Official Symbol of Gene | LOC102724971 |
| Species | Homo sapiens |
| Entrez Gene ID | 102724971 |
| Official Full Name | NA |
| Also known as | IGH; IgA; IGH@; IGVH; ighv; IGHV4; IGHV@; V4-4b; IGHV4-4; IGHV4-04 |
| Gene Type | protein coding |
| dbXrefs | NA |
| Map Location | 15q11.2 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | CSF |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | NA |
| Sample Size | 12MS/15OND |
Literature information of multiple sclerosis :
| Pubmed ID | 9727074 |
| Year | 1998 |
| Title | Clonal Expansion and Somatic Hypermutation of V H Genes of B Cells from Cerebrospinal Fluid in Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | Our results demonstrate that in MS CSF, there is a high frequency of clonally expanded B cells that have properties of postgerminal center memory or antibody-forming lymphocytes. |
| Mechanism/Pathway | The cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients is characterized by increased concentrations of immunoglobulin (Ig), which on electrophoretic analysis shows restricted heterogeneity (oligoclonal bands). |
