Basic information of CYTH4 :
| Official Symbol of Gene | CYTH4 |
| Species | Homo sapiens |
| Entrez Gene ID | 27128 |
| Official Full Name | cytohesin 4 |
| Also known as | CYT4; PSCD4; DJ63G5.1; cytohesin-4 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000100055 MIM:606514; AllianceGenome:HGNC:9505 |
| Map Location | 22q13.1 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | NA |
| Sample Size | 272MS/420Health |
Literature information of multiple sclerosis :
| Pubmed ID | 25823437 |
| Year | 2015 |
| Title | Dominant and Protective Role of the CYTH4 Primate-Specific GTTT-Repeat Longer Alleles Against Neurodegeneration |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | indicating a dominant and protective effect for the longer alleles against neurodegeneration. |
| Mechanism/Pathway | The longest tetra-nucleotide repeat identified in a human gene core promoter belongs to the CYTH4 gene. This GTTT-repeat is specific to Hominidae and Old World monkeys, and the shortest allele of this repeat, (GTTT)6, i s l i n k e d w i t h n e u r a l dysfunction and type I bipolar disorder in human. |
