Basic information of TAP2 :
| Official Symbol of Gene | TAP2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6891 |
| Official Full Name | transporter 2, ATP binding cassette subfamily B member |
| Also known as | APT2; PSF2; ABC18; ABCB3; PSF-2; RING11; D6S217E |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000204267 MIM:170261; AllianceGenome:HGNC:44 |
| Map Location | 6p21.32 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Australian |
| Sample Size | 100RRMS/100Health |
Literature information of multiple sclerosis :
| Pubmed ID | 7797612 |
| Year | 1995 |
| Title | TAP2 polymorphisms in Australian multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The results of this study exclude TAP2 as a locus for a necessary MS/MHC gene but indicate that an MS gene carried by the DRBl* 1501, DQAl * 0102, DQBl* 0602 haplotype could reside centromeric of DQ. |
| Mechanism/Pathway | Polymorphism of the TAP2 gene locus, situated approximately 150 kb centromeric to the MHC class II loci HLA-DR, DQ was examined in 100 Australian patients with relapsing/remitting multiple sclerosis (MS), in 100 random controls and in 37 selected HLA-DRBl* 1501-positive controls. |
