Basic information of TRBV20OR9-2 :
| Official Symbol of Gene | TRBV20OR9-2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6962 |
| Official Full Name | T cell receptor beta variable 20/OR9-2 (non-functional) |
| Also known as | TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O |
| Gene Type | pseudo |
| dbXrefs | Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197 |
| Map Location | 9p13.3 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 9MS/30Health |
Literature information of multiple sclerosis :
| Pubmed ID | 9138431 |
| Year | 1997 |
| Title | Limited Junctional Diversity of 5-J b I Rearrangement in Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The clonal nature of this rearrangement proved by PAGE and sequencing analysis may suggest an antigen- driven expansion of 76T cells and argues for a significant role of 7~ T-cells with V65-J61 rearrangement in MS pathogenesis. |
| Mechanism/Pathway | T-cell receptor (TCR) 6 gene repertoire, as assessed by V~-J6 re- arrangements, has been analyzed in nine multiple sclerosis (MS) cases and in 30 healthy individuals by seminested PCR technique. |
