Basic information of TRBV20OR9-2 :
| Official Symbol of Gene | TRBV20OR9-2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6962 |
| Official Full Name | T cell receptor beta variable 20/OR9-2 (non-functional) |
| Also known as | TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O |
| Gene Type | pseudo |
| dbXrefs | Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197 |
| Map Location | 9p13.3 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Australian |
| Sample Size | 122MS/96Health |
Literature information of multiple sclerosis :
| Pubmed ID | 10871824 |
| Year | 2000 |
| Title | T cell receptor b chain genotyping in Australian relapsing-remitting multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | These results support the involvement of the TCRB region in MS susceptibility and encourage further study of the variable gene segments in this region |
| Mechanism/Pathway | This study focused on susceptibility to MS within the b-chain of the T-cell antigen receptor (TCRB locus, 7q35) in a cohort of 122 RR-MS patients compared with 96 normal individuals using biallelic polymorphisms across the bv8s1(Vb8.1) to bv11s1 (Vb11) TCRB subregion. |
