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Basic information of GSTT1 :

Official Symbol of Gene GSTT1
Species Homo sapiens
Entrez Gene ID 2952
Official Full Name glutathione S-transferase theta 1
Also known as NA
Gene Type protein coding
dbXrefs MIM:600436
Map Location 22q11.23
Variation Type Allele
refSNP ID NA

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype MS
Population Greek patients
Sample Size 47MS/165Health

Literature information of multiple sclerosis :

Pubmed ID 17437619
Year 2007
Title Glutathione-S-transferase T1 and M1 gene polymorphisms in Greek patients with multiple sclerosis: a pilot study

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result The results suggest that GSTT1 and GSTM1 have no major pathogenetic role on the MS occurrence, nor any strong modifying effect on the disability status
Mechanism/Pathway Glutathione-S-transferases (GSTs) are detoxification enzymes, evolved to protect cells against reactive oxygen metabolites.