Basic information of GSTM1 :
| Official Symbol of Gene | GSTM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 2944 |
| Official Full Name | glutathione S-transferase mu 1 |
| Also known as | MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134184 MIM:138350; AllianceGenome:HGNC:4632 |
| Map Location | 1p13.3 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Greek patients |
| Sample Size | 47MS/165Health |
Literature information of multiple sclerosis :
| Pubmed ID | 17437619 |
| Year | 2007 |
| Title | Glutathione-S-transferase T1 and M1 gene polymorphisms in Greek patients with multiple sclerosis: a pilot study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The results suggest that GSTT1 and GSTM1 have no major pathogenetic role on the MS occurrence, nor any strong modifying effect on the disability status |
| Mechanism/Pathway | Glutathione-S-transferases (GSTs) are detoxification enzymes, evolved to protect cells against reactive oxygen metabolites. |
