Basic information of CD40 :
| Official Symbol of Gene | CD40 |
| Species | Homo sapiens |
| Entrez Gene ID | N/A |
| Official Full Name | CD40 molecule |
| Also known as | p50; Bp50; CDW40; TNFRSF5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000101017 MIM:109535; AllianceGenome:HGNC:11919 |
| Map Location | 20q13.12 |
| Variation Type | SNP |
| refSNP ID | rs1883832 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Spanish |
| Sample Size | 1564MS/2948Control |
Literature information of multiple sclerosis :
| Pubmed ID | 20634952 |
| Year | 2010 |
| Title | CD40:Novel Association with Crohn’s Disease and Replication in Multiple Sclerosis Susceptibility |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The impact of CD40 rs1883832 on MS and CD risk points to a common signaling shared by these autoimmune conditions. |
| Mechanism/Pathway | A functional polymorphism located at 21 from the start codon of the CD40 gene, rs1883832, was previously reported to disrupt a Kozak sequence essential for translation. |
