Basic information of VDR :
| Official Symbol of Gene | VDR |
| Species | Homo sapiens |
| Entrez Gene ID | 7421 |
| Official Full Name | vitamin D receptor |
| Also known as | NR1I1; PPP1R163 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679 |
| Map Location | 12q13.11 |
| Variation Type | SNP |
| refSNP ID | rs7975232 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | real-time PCR using TaqMan probes |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Caucasian origin from southern Spain |
| Sample Size | 209 patients/836 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 33044390 |
| Year | 2021 |
| Title | Association between polymorphisms in the vitamin D receptor and susceptibility to multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | Negative |
| Result | We found no influence of the ApaI (rs7975232), BsmI (rs1544410), Cdx2 (rs11568820), FokI (rs2228570), and TaqI (rs731236) gene polymorphisms on the risk of developing MS in our patients. |
| Mechanism/Pathway | Vitamin D metabolism |
