Basic information of BDNF :
| Official Symbol of Gene | BDNF |
| Species | Homo sapiens |
| Entrez Gene ID | 627 |
| Official Full Name | brain derived neurotrophic factor |
| Also known as | ANON2; BULN2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000176697 MIM:113505; AllianceGenome:HGNC:1033 |
| Map Location | 11p14.1 |
| Variation Type | SNP |
| refSNP ID | rs6265 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | MX4000 (Stratagene) real-time thermal cycler |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 209 consecutive patients |
Literature information of multiple sclerosis :
| Pubmed ID | 20478698 |
| Year | 2011 |
| Title | Effect of Met66 allele of the BDNF rs6265 SNP on regional gray matter volumes in patients with multiple sclerosis: A voxel-based morphometry study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | Based on the overlapping regions from the VBM and TFCE method, we surmise that regions in the cingulate have higher GM volumes in MS patients with the Met66 allele of BDNF. |
| Mechanism/Pathway | N/A |
