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Basic information of HLA-G :

Official Symbol of Gene HLA-G
Species Homo sapiens
Entrez Gene ID 3135
Official Full Name major histocompatibility complex, class I, G
Also known as MHC-G
Gene Type protein coding
dbXrefs Ensembl:ENSG00000204632 MIM:142871; AllianceGenome:HGNC:4964
Map Location 6p22.1
Variation Type The -725 C/G exchange in the HLA-G promoter region
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method TaqMan
Disease MS
Disease subtype N/A
Population N/A
Sample Size 698MS patients and 272 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 17462509
Year 2007
Title The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis

Results of multiple sclerosis :

Risk Type N/A
Main Result negative
Result No association was seen with the age of onset of disease, disease severity or disease course. Although HLA-G is assumed to play an important role in the immunoregulatory processes of MS, our results do not support a role of genetic factors influencing disease susceptibility of the disease course.
Mechanism/Pathway N/A