Home Details
| Official Symbol of Gene | HLA-G |
| Species | Homo sapiens |
| Entrez Gene ID | 3135 |
| Official Full Name | major histocompatibility complex, class I, G |
| Also known as | MHC-G |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000204632 MIM:142871; AllianceGenome:HGNC:4964 |
| Map Location | 6p22.1 |
| Variation Type | The -725 C/G exchange in the HLA-G promoter region |
| refSNP ID | N/A |
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 698MS patients and 272 healthy controls |
| Pubmed ID | 17462509 |
| Year | 2007 |
| Title | The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis |
| Risk Type | N/A |
| Main Result | negative |
| Result | No association was seen with the age of onset of disease, disease severity or disease course. Although HLA-G is assumed to play an important role in the immunoregulatory processes of MS, our results do not support a role of genetic factors influencing disease susceptibility of the disease course. |
| Mechanism/Pathway | N/A |

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