Basic information of APOE :

Official Symbol of Gene	APOE
Species	Homo sapiens
Entrez Gene ID	348
Official Full Name	apolipoprotein E
Also known as	AD2; LPG; APO-E; ApoE4; LDLCQ5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613
Map Location	19q13.32
Variation Type	SNP
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	Blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	66 patients, 45 carried the 13/13 genotype, 15 the 13/12 and six the 13/14

Literature information of multiple sclerosis :

Pubmed ID	11109009
Year	2000
Title	Association of apolipoprotein E polymorphism to clinical heterogeneity of multiple sclerosis

Results of multiple sclerosis :

Risk Type	N/A
Main Result	negative
Result	Later onset of chronic progressive MS was observed in patients carrying the epsilon2 allele, whereas APO E alleles were found at similar frequency in MS and in the control population.These findings indicate that clinical heterogeneity, but probably not susceptibility to the disease, is associated to APO E genotypes.
Mechanism/Pathway	N/A