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Basic information of Tcrb :

Official Symbol of Gene Tcrb
Species Mus musculus
Entrez Gene ID 21577
Official Full Name T cell receptor beta chain
Also known as Tib; TCRbeta
Gene Type protein coding
dbXrefs MGI:MGI:98578
Map Location 6 B1; 6
Variation Type Tcrb haplotype
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample Spinal Cord
Sample Detail N/A
Detected Method flow cytometric,immunizing with mouse spinal-cord homogenate
Disease EAE
Disease subtype N/A
Population H-2r mice,RIIIS/J mouse
Sample Size 140 mice

Literature information of multiple sclerosis :

Pubmed ID 7679665
Year 1993
Title Influence of T-cell receptor genes on chronic experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Risk Type N/A
Main Result negative
Result Fluorescence-activated cell sorter (FACS) analyses of lymphoid cells from the F2 mice showed that the Tcrb haplotypes did not correlate with signs of encephalomyelitis (Fig. 1 and Table 2),and therefore appeared to have no or simply a minor genetic influence on disease development.
Mechanism/Pathway N/A