Basic information of HLA-DPB1 :
| Official Symbol of Gene | HLA-DPB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3115 |
| Official Full Name | major histocompatibility complex, class II, DP beta 1 |
| Also known as | DPB1; HLA-DP; HLA-DPB; HLA-DP1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940 |
| Map Location | 6p21.32 |
| Variation Type | polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | southwest of France |
| Sample Size | multiple sclerosis (n = 112) and in healthy controls (n = 115) |
Literature information of multiple sclerosis :
| Pubmed ID | 1918327 |
| Year | 1991 |
| Title | HLA-DPB1 gene polymorphism and multiple sclerosis: a large case-control study in the southwest of France |
Results of multiple sclerosis :
| Risk Type | N/A |
| Main Result | negative |
| Result | The distribution of the DPB1 alleles was not significantly different in multiple sclerosis patients and controls (p = 0.11). |
| Mechanism/Pathway | The associations may be due to a pathogenic effect of the HLA antigens themselves or to linkage disequilibrium between the HLA genes and a closely located susceptibility gene. |
