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Basic information of TRB :

Official Symbol of Gene TRB
Species Homo sapiens
Entrez Gene ID 6957
Official Full Name T cell receptor beta locus
Also known as TCRB; TRB@
Gene Type protein coding
dbXrefs AllianceGenome:HGNC:12155
Map Location 7q34
Variation Type polymorphism
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample Blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size Ninety-six individuals were examined, and 34 had clinically definite or laboratory-supported definite MS.

Literature information of multiple sclerosis :

Pubmed ID 1683213
Year 1991
Title Discordance of T-cell receptor beta-chain genes in familial multiple sclerosis

Results of multiple sclerosis :

Risk Type N/A
Main Result negative
Result For the autosomal recessive model with a penetrance range from 0.1 to 1.0, the LOD scores ranged from -8.20 to -32.98. These findings do not support a direct role of T-cell receptor beta-chain gene in the inheritance of MS.
Mechanism/Pathway N/A