Basic information of C3 :
| Official Symbol of Gene | C3 |
| Species | Homo sapiens |
| Entrez Gene ID | 718 |
| Official Full Name | complement C3 |
| Also known as | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125730 MIM:120700; AllianceGenome:HGNC:1318 |
| Map Location | 19p13.3 |
| Variation Type | polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | horizontal high voltage agarose gel electrophoresis |
| Disease | MS |
| Disease subtype | N/A |
| Population | Danish |
| Sample Size | 60 patients with multiple sclerosis (M.S.),1066 apparently healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 7211174 |
| Year | 1980 |
| Title | C3 polymorphism and circulating immune complexes in patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | A significantly increased frequency of the C3F-gene was found among the patients, and closely associated with the occurrence of CIC. |
| Mechanism/Pathway | A possible explanation involves the hypothesis, that the patients with low C3 levels, but without detectable CIC, could suffer from a type 11 reaction disease. |
