Basic information of IL18 :
| Official Symbol of Gene | IL18 |
| Species | Homo sapiens |
| Entrez Gene ID | 3606 |
| Official Full Name | interleukin 18 |
| Also known as | IGIF; IL-18; IL-1g; IL1F4 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000150782 MIM:600953; AllianceGenome:HGNC:5986 |
| Map Location | 11q23.1 |
| Variation Type | SNP |
| refSNP ID | rs1946518 C/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Egyptian |
| Sample Size | 93 patients with MS and 57 unrelated healthy subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 33302229 |
| Year | 2020 |
| Title | Polymorphisms in proinflammatory cytokines genes and susceptibility to Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | The TNF-α-308 AA genotype and A allele could be related to disability progression and severity of MS and the IL-18-607 AA genotype A allele could be related to susceptibility of the disease in the Egyptian cohort. |
| Mechanism/Pathway | N/A |
