Basic information of FOXO3 :
| Official Symbol of Gene | FOXO3 |
| Species | Homo sapiens |
| Entrez Gene ID | 2309 |
| Official Full Name | forkhead box O3 |
| Also known as | FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118689 MIM:602681; AllianceGenome:HGNC:3821 |
| Map Location | 6q21 |
| Variation Type | SNP |
| refSNP ID | rs4966936 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 79 RRMS patients and 104 healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 31759981 |
| Year | 2020 |
| Title | The effect of FOXO gene family variants and global DNA metylation on RRMS disease |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | In addition, it has been determined that variants of FOXO3a (rs2253310, rs4966936) and FOXO1 (rs3900833), which have been genotyped, may be effective in disease pathogenesis. |
| Mechanism/Pathway | N/A |
