Basic information of PDCD1 :
| Official Symbol of Gene | PDCD1 |
| Species | Homo sapiens |
| Entrez Gene ID | 5133 |
| Official Full Name | programmed cell death 1 |
| Also known as | PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; Hsle1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000188389 MIM:600244; AllianceGenome:HGNC:8760 |
| Map Location | 2q37.3 |
| Variation Type | SNP |
| refSNP ID | rs2227981 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | SPMS,RRMS |
| Population | south Polish |
| Sample Size | 203 unrelated MS patients,276 healthy volunteers |
Literature information of multiple sclerosis :
| Pubmed ID | 28284331 |
| Year | 2017 |
| Title | PD-1 gene polymorphic variation is linked with first symptom of disease and severity of relapsing-remitting form of MS |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | Our population-based case-control study, investigating selected three PD-1 SNPs: PD-1.3, PD-1.5 and PD-1.9, revealed that polymorphic variation may be rather disease-modifying than MS risk factor. |
| Mechanism/Pathway | N/A |
