Basic information of GRN :
| Official Symbol of Gene | GRN |
| Species | Homo sapiens |
| Entrez Gene ID | 2896 |
| Official Full Name | granulin precursor |
| Also known as | GEP; GP88; PEPI; PGRN; CLN11; PCDGF |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000030582 MIM:138945; AllianceGenome:HGNC:4601 |
| Map Location | 17q21.31 |
| Variation Type | SNP |
| refSNP ID | rs2879096 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | PPMS |
| Population | N/A |
| Sample Size | 354 patients,343 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20463744 |
| Year | 2010 |
| Title | Progranulin gene variability increases the risk for primary progressive multiple sclerosis in males |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | An association with the rs2879096T allele was observed (29.2 in patients compared with 18.9% in controls, P=0.012, OR 1.77, 95% CI 1.1-2.8). |
| Mechanism/Pathway | N/A |
