Home Details
| Official Symbol of Gene | SPARCL1 |
| Species | Homo sapiens |
| Entrez Gene ID | 8404 |
| Official Full Name | SPARC like 1 |
| Also known as | SC1; MAST9; PIG33; MAST 9 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000152583 MIM:606041; AllianceGenome:HGNC:11220 |
| Map Location | 4q22.1 |
| Variation Type | SNP |
| refSNP ID | rs1049539 |
| Detected Sample | cerebrospinal fluid |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | One hundred eighty-six patients with MS,185 subjects |
| Pubmed ID | 17825989 |
| Year | 2007 |
| Title | Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis |
| Risk Type | N/A |
| Main Result | negative |
| Result | One hundred eighty-six patients with MS and 185 age-matched controls were genotyped for A/G single nucleotide polymorphism (SNP) in exon 1 (rs1049539), C/G SNP in exon 4 (rs1049544), resulting in a substitution of an aspartate with an histidine, and A/G substitution in the exon 5 (rs1130643), leading to the substitution of alanine with threonine. No significant differences in either allelic or genotypic frequency of the three SNPs were found (P>0.05), even in stratifying MS patients according to the course of the disease. |
| Mechanism/Pathway | N/A |

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