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Basic information of SPARCL1 :

Official Symbol of Gene SPARCL1
Species Homo sapiens
Entrez Gene ID 8404
Official Full Name SPARC like 1
Also known as SC1; MAST9; PIG33; MAST 9
Gene Type protein coding
dbXrefs Ensembl:ENSG00000152583 MIM:606041; AllianceGenome:HGNC:11220
Map Location 4q22.1
Variation Type SNP
refSNP ID rs1130643

Sample information of multiple sclerosis:

Detected Sample cerebrospinal fluid
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size One hundred eighty-six patients with MS,185 subjects

Literature information of multiple sclerosis :

Pubmed ID 17825989
Year 2007
Title Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis

Results of multiple sclerosis :

Risk Type N/A
Main Result negative
Result One hundred eighty-six patients with MS and 185 age-matched controls were genotyped for A/G single nucleotide polymorphism (SNP) in exon 1 (rs1049539), C/G SNP in exon 4 (rs1049544), resulting in a substitution of an aspartate with an histidine, and A/G substitution in the exon 5 (rs1130643), leading to the substitution of alanine with threonine. No significant differences in either allelic or genotypic frequency of the three SNPs were found (P>0.05), even in stratifying MS patients according to the course of the disease.
Mechanism/Pathway N/A