Basic information of HLA-DPB1 :
| Official Symbol of Gene | HLA-DPB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3115 |
| Official Full Name | major histocompatibility complex, class II, DP beta 1 |
| Also known as | DPB1; HLA-DP; HLA-DPB; HLA-DP1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DPB1*1801 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood leukocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Japanese |
| Sample Size | 44 MS patients and 140 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1286977 |
| Year | 1992 |
| Title | HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. |
| Mechanism/Pathway | These results suggest that MS susceptibility may result from polygenic influences and from the presence of environmental factors. |
