Basic information of TNFRSF1A :
| Official Symbol of Gene | TNFRSF1A |
| Species | Homo sapiens |
| Entrez Gene ID | 7132 |
| Official Full Name | TNF receptor superfamily member 1A |
| Also known as | FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000067182 MIM:191190; AllianceGenome:HGNC:11916 |
| Map Location | 12p13.31 |
| Variation Type | SNP |
| refSNP ID | rs1800693 |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | RRMS |
| Population | European |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 22801493 |
| Year | 2012 |
| Title | TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | By analysing MS GWAS data in conjunction with the 1000 Genomes Project data we provide genetic evidence that strongly implicates this SNP, rs1800693, as the causal variant in the TNFRSF1A region. |
| Mechanism/Pathway | N/A |
