Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | HLA-DRB1 *0801 allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | sequencing-based method |
| Disease | MS |
| Disease subtype | LOMS |
| Population | Western Australia |
| Sample Size | 1004 patients |
Literature information of multiple sclerosis :
| Pubmed ID | 20580995 |
| Year | 2010 |
| Title | Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | HLA-DRB1 *1501 was strongly associated with both LOMS and EOMS compared to the Control subjects, while HLA-DRB1 *0801 was over-represented in patients with LOMS. |
| Mechanism/Pathway | N/A |
