Basic information of HLA-DQA1 :
| Official Symbol of Gene | HLA-DQA1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3117 |
| Official Full Name | major histocompatibility complex, class II, DQ alpha 1 |
| Also known as | DQA1; DQ-A1; CELIAC1; HLA-DQA; HLA-DQB1; HLA-DQA1* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196735 MIM:146880; AllianceGenome:HGNC:4942 |
| Map Location | 6p21.32 |
| Variation Type | DQA1*0102 |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | polymerase chain reaction and sequence-specific oligonucleotide probe hybridization |
| Disease | MS |
| Disease subtype | N/A |
| Population | Israel |
| Sample Size | 104 Ashkenazi (80 with a relapsing remitting or secondary progressive and 24 with a primary chronic progressive course of the disease) and 58 non-Ashkenazi (36 with a relapsing remitting or secondary progressive course and 22 with a primary chronic progressive course of the disease), matched with 132 Ashkenazi and 120 non-Ashkenazi healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10328250 |
| Year | 1999 |
| Title | HLA class II susceptibility to multiple sclerosis among Ashkenazi and non-Ashkenazi Jews |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | The haplotype DRB1*1501, DQA1*0102, DQB1*0602 was found to be associated with MS among both Ashkenazi and non-Ashkenazi patients (P<.001 and P =.04, respectively). |
| Mechanism/Pathway | N/A |
