Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | DRB5 * 0101 |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | Blood |
| Sample Detail | N/A |
| Detected Method | PCR-SSOP |
| Disease | MS |
| Disease subtype | N/A |
| Population | French Canadians |
| Sample Size | 78 French Canadian multiple sclerosis (MS) patients and 79 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1429036 |
| Year | 1992 |
| Title | Contribution of a single DQ beta chain residue to multiple sclerosis in French Canadians |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | positive |
| Result | In this relatively homogeneous ethnic group, MS was positively associated with DRB5*0101, DQB1*0602, and DQA1*0102 and negatively associated with DQB1*0301. |
| Mechanism/Pathway | N/A |
